Antitubercular agent-27 (compound 1) is a potent antitubercular agent with an IC 50 value of 3.2 µM, an MIC value of 7.8 µM, an IC 90 value of 7.0 µM. Antitubercular agent-27 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv . Antitubercular agent-27 shows effective intracellular antimycobacterial activity and low cytotoxicity.
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