RNA polymerase II-IN-2

Overview

RNA polymerase II-IN-2 is a RNA polymerase II inhibitor with a K i value of 74.1 nM. RNA polymerase II-IN-2 inhibits Pol II -mediated transcription and induces cytotoxicity in mammalian cells. RNA polymerase II-IN-2 serves as a payload for antibody-drug conjugates ( ADC ) and is applicable for cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-147917
• CAS No.: 2891451-33-3
• Molecular Formula: C41H58N10O12S
• Molecular Weight: 915.02
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source