(S)-GSK-F1

Overview

(S)-GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α ( PI4KIIIα ). (S)-GSK-F1 inhibits PI4Kα, PI4Kβ, PI4Kγ, PI3Kα , PI3Kβ and PI3Kδ with pIC 50 of 8.3, 6.0, 5.6, 5.6, 5.1 and 5.6, respectively. (S)-GSK-F1 exhibits anti-hepatitis C virus ( HCV ) activity through inhibition of HCV replication. (S)-GSK-F1 exhibits moderate pharmacokinetic characters in rat model.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Infection | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > PI4K

Product Information

• Catalog No.: HY-100603A
• CAS No.: 1384097-27-1
• Molecular Formula: C27H18F5N5O4S
• Molecular Weight: 603.52
• Purity: 98.01%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source