VU0483605

Overview

VU0483605 is a potent and brain-penetrated mGlu 1 receptor positive allosteric modulator (PAM). VU0483605 shows excellent mGlu 1 PAM activity at both human and rat, with EC 50 values of 390 and 356 nM, respectively.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Others | Products > Signaling Pathways > mGluR

Product Information

• Catalog No.: HY-100605
• CAS No.: 1623101-11-0
• Molecular Formula: C20H10Cl3N3O3
• Molecular Weight: 446.67
• Purity: 97.30%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution
• Availability: In-stock

Source

Original product source