Tecovirimat-d 4

Overview

Tecovirimat -d 4 (ST-246-d 4 ) is a deuterium-labelled Tecovirimat ( HY-14805 ). Tecovirimat is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC 50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene , which is homologous to vaccinia virus F13L , encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat could be used in the study for orthopoxvirus-induced diseases.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Others | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Orthopoxvirus | Products > Signaling Pathways > Arenavirus

Product Information

• Catalog No.: HY-14805S
• CAS No.: 2923753-84-6
• Molecular Formula: C19H11D4F3N2O3
• Molecular Weight: 380.35
• Purity: 98.95%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source