DB1113

Overview

DB1113 (Example 24) is a bifunctional compound targeted protein degradation of kinases. DB1113 degrades ABL1 , ABL2, BLK , CDK11B, CDK4 , CSK, EPHA3 , FER, GAK, LIMK1 , MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2 , MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1 , RPS6KA1, RPS6KA3, SIK2 , SIK3 , STK35, TNK2, and ULK1 . DB1113 can be used for research of disease or disorder mediated by aberrant kinase activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Salt-inducible Kinase (SIK) | Products > Signaling Pathways > Cyclin G-associated Kinase (GAK) | Products > Signaling Pathways > MAP4K | Products > Signaling Pathways > MAPKAPK2 (MK2) | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > ULK | Products > Signaling Pathways > LIM Kinase (LIMK) | Products > Signaling Pathways > PROTACs

Product Information

• Catalog No.: HY-148061
• CAS No.: 2769753-53-7
• Molecular Formula: C59H68F3N13O6S
• Molecular Weight: 1144.31
• Purity: 99.22%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source