BAY-390

Overview

BAY-390, a chemical probe, is a selective, across species active and brain penetrating TRPA1 inhibitor. BAY-390 inhibits hTRPA1 FLIPR, hTRPA1 Ephys, rTRPA1 FLIPR and rDRG Ephys with IC 50 s of 16, 82, 63 and 35 nM, respectively. BAY-390 can be used for the research of inflammation.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-148236
• CAS No.: 2741956-55-6
• Molecular Formula: C13H15F4NO
• Molecular Weight: 277.26
• Purity: 99.74%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (9.02 mM); Clear solution
• Availability: In-stock

Source

Original product source