BMS-986020

Overview

BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1 ) antagonist. BMS-986020 inhibits bile acid and phospholipid transporters with IC 50 s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively. BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF).

Application

Products | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > LPL Receptor

Product Information

• Catalog No.: HY-100619
• CAS No.: 1257213-50-5
• Molecular Formula: C29H26N2O5
• Molecular Weight: 482.53
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.31 mM); Clear solution
• Availability: In-stock

Source

Original product source