Lesogaberan hydrochloride (Standard)

Overview

Lesogaberan (hydrochloride) (Standard) is the analytical standard of Lesogaberan (hydrochloride) ( HY-10061B ). This product is intended for research and analytical applications. Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptor. The affinity (Kis) of Lesogaberan hydrochloride for rat GABAB and GABAA receptors, as measured by displacement of [3H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GABA Receptor | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-10061BR
• CAS No.: 2925644-17-1
• Molecular Formula: C3H10ClFNO2P
• Molecular Weight: 177.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source