TUG-499

Overview

TUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) ( Free Fatty Acid Receptor ) agonist with a pEC 50 of 7.39. TUG-499 exhibits >100-fold selectivity over the related receptors FFA2, FFA3, and the nuclear receptor PPARγ and other diverse receptors, ion channels, and transporters. TUG-499 can be used for the research of type 2 diabetes. TUG-499 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Glucose Metabolism | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Free Fatty Acid Receptor

Product Information

• Catalog No.: HY-148418
• CAS No.: 1206629-08-4
• Molecular Formula: C16H11Cl2NO2
• Molecular Weight: 320.17
• Purity: 99.78%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.81 mM); Clear solution
• Availability: In-stock

Source

Original product source