NDH-1 inhibitor-1 is a NADH-ubiquinone oxidoreductase ( NDH-1 ) inhibitor with a pIC 50 of 5.40 in potato tuber mitochondria and a pIC 50 of 6.15 in Escherichia coli cell membranes. NDH-1 inhibitor-1 acts on the ubiquinone catalytic site to inhibit enzyme activity. NDH-1 inhibitor-1 can be used to study pathogenic microbial infections or mitochondrial diseases.
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