Ispronicline

Overview

Ispronicline (TC-1734), an orally active, brain-selective α4β2 nicotine acetylcholine receptor ( nAChR ) partial agonist, has shown memory-enhancing properties in rodents and a good tolerability profile. Ispronicline binds to the α4β2 nAChR with high affinity ( K i =11 nM) and is highly selective to other nAChRs such as α7 nAChR and α3β4 nAChR .

Application

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Product Information

• Catalog No.: HY-10063
• CAS No.: 252870-53-4
• Molecular Formula: C14H22N2O
• Molecular Weight: 234.34
• Purity: 98.24%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (10.67 mM); Clear solution
• Availability: In-stock

Source

Original product source