LAS190792

Overview

LAS190792 is a bifunctional muscarinic acetylcholine receptor ( mAChR ) antagonist and β2- adrenergic receptor agonist. LAS190792 has a pIC 50 of 8.8 against human M3 muscarinic receptor and a pIC 50 of 9.1 against human β2-adrenergic receptor. LAS190792 exhibits vasodilatory and anti-inflammatory activities, and induces sustained bronchodilation in dogs. LAS190792 inhibits the release of IL-8 , MMP9 , IL-1β and GM-CSF from lipopolysaccharide-stimulated neutrophils. LAS190792 can be used in research related to respiratory system diseases.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > mAChR | Products > Signaling Pathways > Adrenergic Receptor | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-148527
• CAS No.: 1347232-69-2
• Molecular Formula: C39H43ClN4O9S2
• Molecular Weight: 811.36
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source