Tafamidis-d 3 is deuterium labeled Tafamidis. Tafamidis is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC 50 s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Others | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Transthyretin (TTR) | Products > Signaling Pathways > Isotope-Labeled Compounds
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