Tecarfarin sodium

Overview

Tecarfarin (ATI-5923) sodium is an orally active VKOR inhibitor with an IC 50 of 0.67 μM against VKORC1 . Tecarfarin sodium blocks the post-translational modification of vitamin K-dependent coagulation factors II, VII, IX and X, reducing their levels and activities. Tecarfarin sodium prolongs prothrombin time, attenuates venous and arterial thrombosis, increases ear incision bleeding volume, and exerts reversible anticoagulant effects. Tecarfarin sodium is applicable to research related to arterial and venous thrombosis as well as other diseases requiring anticoagulation.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > VKOR

Product Information

• Catalog No.: HY-14854A
• CAS No.: 1004551-83-0
• Molecular Formula: C21H13F6NaO5
• Molecular Weight: 482.31
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source