MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan

Overview

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC , consisting Exatecan ( HY-13631 ). Exatecan is a DNA Topoisomerase I inhibitor (IC 50 =2.2 μM).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug-Linker Conjugates for ADC | Products > Signaling Pathways > Topoisomerase

Product Information

• Catalog No.: HY-148668
• CAS No.: 2414254-51-4
• Molecular Formula: C55H60FN9O13
• Molecular Weight: 1074.12
• Purity: 95.08%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (2.33 mM); Clear solution
• Availability: In-stock

Source

Original product source