Nimucitinib

Overview

Nimucitinib is a selective JAK inhibitor with potent tear secretion-promoting activity. Nimucitinib downregulates relevant signal transduction pathways by inhibiting the catalytic activity of JAK family tyrosine kinases. Nimucitinib promotes tear secretion in rabbits and inhibits corneal injury in rats. Nimucitinib can be used in dry eye-related research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Dry Eye Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-148785
• CAS No.: 2740557-24-6
• Molecular Formula: C25H26F2N6O2
• Molecular Weight: 480.51
• Purity: 99.27%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source