SRI-42127

Overview

SRI-42127 is a HuR translocation inhibitor. HuR is an RNA regulator that binds to AREs, and HuR translocations promote the production of inflammatory cytokines in glial cells. However, SRI-42127 can destroy mRNA stability and inhibit gene promoter activation. SRI-42127 also inhibits microglial cell activation and attenuates recruitment/chemotaxis of neutrophils and monocytes.

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Others | Products > Signaling Pathways > HuR

Product Information

• Catalog No.: HY-148853
• CAS No.: 2727872-68-4
• Molecular Formula: C19H20N6O
• Molecular Weight: 348.40
• Purity: 99.80%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.97 mM); Clear solution
• Availability: In-stock

Source

Original product source