GLX481372

Overview

GLX481372 is a NADPH Oxidase ( NOX ) inhibitor. GLX481372 potently inhibits NOX4/5 activities with IC 50 values of 0.68 and 0.57 μM. GLX481372 also has weak inhibitory activity against NOX1 , NOX2 , and NOX3, with IC 50 values of 7, 16 and 3.2 μM respectively. GLX481372 can inhibit ROS production. GLX481372 can be used for the researches of inflammation, cardiovascular and metabolic disease , such as diabetes.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NADPH Oxidase | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-148936
• CAS No.: 1990478-58-4
• Molecular Formula: C23H29N7
• Molecular Weight: 403.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source