Desmethyl cariprazine

Overview

Desmethyl cariprazine is a major active metabolite of cariprazine, with activities at human dopamine receptors and serotonin receptors, showing a pEC 50 of 8.90 at human D2 receptors, a pEC 50 of 8.09 at D3 receptors, and a pEC 50 of 6.28 at 5-HT 1A receptors. Desmethyl cariprazine inhibits forskolin-induced cAMP production at D2 , D3 and 5-HT 1A receptors, and suppresses serotonin-induced Ca 2+ release at 5-HT 2B receptors. Desmethyl cariprazine is applicable to research related to schizophrenia, bipolar disorder type I and bipolar disorder.

Application

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Product Information

• Catalog No.: HY-100656
• CAS No.: 839712-15-1
• Molecular Formula: C20H30Cl2N4O
• Molecular Weight: 413.38
• Purity: 98.08%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source