Antiparasitic agent-16

Overview

Antiparasitic agent-16, a pyridine-thiazolidinone, has anti-Trypanosoma cruzi and leishmanicidal activities. Antiparasitic agent-16 has IC 50 s of 1.0 μM and 0.6 μM against trypomastigote and amastigote forms of T. cruzi . Antiparasitic agent-16 has IC 50 s of 150.2 μM and 16.75 μM against trypomastigote and amastigote forms of L. amazonensis . Antiparasitic agent-16 induces parasite cell death through necrosis induction. Antiparasitic agent-16 induces morphological changes such as shortening, retraction and curvature of the parasite body and leakage of internal content with T. cruzi trypomastigotes.

Application

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Product Information

• Catalog No.: HY-149080
• CAS No.: 3046451-89-9
• Molecular Formula: C18H18N4OS
• Molecular Weight: 338.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source