AChE/BChE-IN-12

Overview

AChE/BChE-IN-12 (compound 10b), a 3,5-dimethoxy analogue, is a potent AChE , BChE , and β-secretase-1 (BACE-1) inhibitor, with IC 50 values of 2.57, 3.26, and 10.65 μM, respectively. AChE/BChE-IN-12 crosses the blood-brain barrier via passive diffusion and inhibits the self-aggregation of amyloid-β monomers. AChE/BChE-IN-12 can be used for Alzheimer’s disease (AD) research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Beta-secretase | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-149211
• CAS No.: 3075661-19-4
• Molecular Formula: C23H21N3O6
• Molecular Weight: 435.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source