COX-2-IN-30

Overview

COX-2-IN-30 is a benzenesulfonamide derivative, as well as an orally active and dual inhibitor of COX ( IC 50 =49 nM for COX-2 , 10.4 μM for COX-1 ) and 5-LOX ( IC 50 =2.4 μM). COX-2-IN-30 also inhibits transmembrane hCA IX and hCA XII isoform with nanomolar calss K i values. COX-2-IN-30 exhibits analgesic, anti-inflammatory, and ulcerogenic activities, and does not show acute gastric effect.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > COX | Products > Signaling Pathways > Carbonic Anhydrase | Products > Signaling Pathways > LOX-1

Product Information

• Catalog No.: HY-149269
• CAS No.: 1160498-08-7
• Molecular Formula: C17H16N6O3S
• Molecular Weight: 384.41
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source