Migalastat hydrochloride

Overview

Migalastat (GR181413A free base) hydrochloride is an orally active α-galactosidase A molecular chaperone, with an IC 50 value of 0.04 μM for human α-Gal A. Migalastat binds to the active site of certain unstable mutant forms of α-galactosidase A, facilitating their transport to the lysosome. After dissociation in the acidic environment, Migalastat enables the mutant α-galactosidase A to exhibit biological activity.

Application

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Product Information

• Catalog No.: HY-14929A
• CAS No.: 75172-81-5
• Molecular Formula: C6H14ClNO4
• Molecular Weight: 199.63
• Purity: 99.70%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 100 mg/mL (500.93 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source