MKA031 (compound 6y) is a non-competitive MIF inhibitor with an IC 50 value of 1.7 μM. MKA031 (compound 6y) interferes with MIF/AIF interaction, MIF nuclear translocation, and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced dependent cell death. MKA031 can be used in the study of chronic hepatitis C virus infection .
Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Infection | Products > Signaling Pathways > Macrophage migration inhibitory factor (MIF)
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