TNF-α-IN-11

Overview

TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor with a K D value of 12.06 μM. TNF-α-IN-11 binds to TNF-α and blocks the activation of TNF-α-trigged caspase and NF-κB signaling pathway. TNF-α-IN-11 inhibits the phosphorylation of IκBα, as well as the nuclear translocation of NF κB p65. TNF-α-IN-11 can be used for research of TNF-α-mediated autoimmune diseases.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-149331
• CAS No.: 2945197-77-1
• Molecular Formula: C24H26N2O5
• Molecular Weight: 422.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source