Vapitadine hydrochloride

Overview

Vapitadine hydrochloride (Compound 3a) is a selective, orally active and nonsedating antihistamine agent, which exhibits a good binding affinity with human cloned histamine H1 receptor with a K i of 19 nM. Vapitadine hydrochloride decreases the histamine-induced lethality (ED 50 is 0.056-1.2 mg/kg), antagonizes the cutaneous reactions to histamine (ED 50 is 0.51-1.4 mg/kg) in rats.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Histamine Receptor

Product Information

• Catalog No.: HY-14939A
• CAS No.: 279253-83-7
• Molecular Formula: C17H22Cl2N4O
• Molecular Weight: 369.29
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source