CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target ( CYP51/PD-L1 ) inhibitor, with IC 50 values of 0.17 and 0.021 μM, respectively. CYP51/PD-L1-IN-4 exhibits excellent antifungal and antidrug-resistant fungal activity in vitro. CYP51/PD-L1-IN-4 can be used for fungal infections research.
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