(R)-Pirlindole mesylate is selective and reversible a Monoamine oxidase A ( MAO-A ) inhibitor with an IC 50 of 0.43 μM for MAO-A over MAO-B . (R)-Pirlindole mesylate has an antidepressant activity. (R)-Pirlindole mesylate significantly decreases immobility time of the forced swim test and inhibits Reserpine ( HY-N0480 )-induced palpebral ptosis in behavioural mice models. (R)-Pirlindole mesylate can be used for depression research.
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