BI-1622

Overview

BI-1622 is an orally active, potent and highly selective HER2 ( ERBB2 ) inhibitor, with an IC 50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR . BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile.

Application

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Product Information

• Catalog No.: HY-150023
• CAS No.: 2681392-19-6
• Molecular Formula: C26H24N10O2
• Molecular Weight: 508.53
• Purity: 98.02%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source