GSK3739936

Overview

GSK3739936 (BMS-986180) is a potent HIV-1 allosteric integrase inhibitor with an IC 50 value of 11.1 nM and an EC 50 value of 1.7 nM. GSK3739936 is also a weak CYP inhibitor (IC 50 >24.3 μM). GSK3739936 shows favorable pharmacokinetic property in preclinical species with rapid absorption, low to moderate clearance and excellent oral bioavailability.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Infection | Products > Signaling Pathways > HIV | Products > Signaling Pathways > HIV Integrase

Product Information

• Catalog No.: HY-150080
• CAS No.: 1803444-21-4
• Molecular Formula: C34H43FN2O4
• Molecular Weight: 562.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source