HKSOX-1

Overview

HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O 2 •− ) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O 2 •− -mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O 2 •− roles in inflammation, mitochondrial stress, and other physiological processes.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Others | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Fluorescent Dye

Product Information

• Catalog No.: HY-150175
• CAS No.: 1786411-17-3
• Molecular Formula: C23H6F10O11S2
• Molecular Weight: 712.40
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source