SA09-Cu

Overview

SA09-Cu is a noncompetitive and potent NDM-1 inhibitor with an IC 50 of 9.6 nM. SA09-Cu can convert NDM-1 into an inactive state by oxidizing the Zn(II)-thiolate site of the enzyme and avoids to be reduced by intracellular thiols of bacteria. SA09-Cu exhibits excellent inhibition against a series of clinical NDM-1-producing carbapenem-resistant Enterobacteriaceae (CRE) in restoring the Meropenem ( HY-13678 ) effect, and slows down the development of carbapenem resistance.

Application

Products | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Bacterial

Product Information

• Catalog No.: HY-150260
• CAS No.: 155641-16-0
• Molecular Formula: C8H16CuN2O2S4
• Molecular Weight: 364.03
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source