SSR240612

Overview

SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist, with K i s of 0.48 nM and 0.73 nM for B1 kinin receptors of human fibroblast MRC5 and HEK cells expressing human B1 receptors, 481 nM and 358 nM for B2 receptors of guinea pig ileum membranes and CHO cells expressing human B1 receptor, respectively.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Bradykinin Receptor

Product Information

• Catalog No.: HY-15039
• CAS No.: 464930-42-5
• Molecular Formula: C42H53ClN4O7S
• Molecular Weight: 793.41
• Purity: 98.72%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (3.15 mM); Clear solution
• Availability: In-stock

Source

Original product source