DPO-1 (Standard)

Overview

DPO-1 (Standard) is the analytical standard of DPO-1 ( HY-100712 ). This product is intended for research and analytical applications. DPO-1 is a potent Kv1.5 and Kv1.3 (EC50 = 3.1 μM) channels inhibitor with potential immunomodulatory and anti-inflammatory effects. DPO-1 reduces Kv1.3 current density, blunts Ca2+ influx in Ca2+-depleted Jurkat cells, and inhibits IL-2 secretion in activated Jurkat cells. DPO-1 inhibits Uric acid sodium ( HY-B2130A ) (MSU)-induced NLRP3 inflammasome activation by blocking Kv1.5-mediated K+ efflux. DPO-1 can be used for the study of immunologic disorders and atrial fibrillation.

Application

Products | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Others | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > NOD-like Receptor (NLR)

Product Information

• Catalog No.: HY-100712R
• CAS No.: 43077-30-1
• Molecular Formula: C22H29OP
• Molecular Weight: 340.44
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source