CYP3A4-IN-3 is a high-affinity specific inhibitor of cytochrome P450 3A4 ( CYP3A4 ) with the IC 50 value of 0.075 μM. CYP3A4-IN-3 is a ritonavir analogue, but with a simpler structure and twice the inhibitory effect of ritonavir. CYP3A4-IN-3 is used as an antiviral agent and immunosuppressant.
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