SPH3127

Overview

SPH3127 (DRI 18) is a novel, highly potent, and orally active direct renin inhibitor (recombinant human-renin IC 50 =0.4 nM, human plasma renin activity IC 50 =0.45 nM). SPH3127 shows antihypertensive effect and can be used in essential hypertension research.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Hypertension | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Renin

Product Information

• Catalog No.: HY-151111
• CAS No.: 1399849-02-5
• Molecular Formula: C22H32N6O4
• Molecular Weight: 444.53
• Purity: 98.26%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 5 mg/mL (11.25 mM); Clear solution
• Availability: In-stock

Source

Original product source