Lonafarnib

Overview

Lonafarnib (Sch66336) is a potent and orally active, and CNS-penetrant farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras , K-ras and N-ras with IC 50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

Application

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Product Information

• Catalog No.: HY-15136
• CAS No.: 193275-84-2
• Molecular Formula: C27H31Br2ClN4O2
• Molecular Weight: 638.82
• Purity: 99.85%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (3.91 mM); Clear solution
• Availability: In-stock

Source

Original product source