MLKL-IN-3

Overview

MLKL-IN-3 (compound 66) is a potent MLKL ( Mixed lineage kinase domain-like protein) inhibitor. MLKL-IN-3 inhibits necroptosis in HT-29 cells and acts downstream of MLKL phosphorylation, with EC 50 of 31 nM. MLKL-IN-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Mixed Lineage Kinase | Products > Signaling Pathways > Necroptosis

Product Information

• Catalog No.: HY-151541
• CAS No.: 3031406-27-3
• Molecular Formula: C31H29ClN4O6
• Molecular Weight: 589.04
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source