Monomethyl auristatin E

Overview

Monomethyl auristatin E (MMAE; SGD-1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types.

Application

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Product Information

• Catalog No.: HY-15162
• CAS No.: 474645-27-7
• Molecular Formula: C39H67N5O7
• Molecular Weight: 717.98
• Purity: 99.97%
• Storage: -20°C, sealed storage, away from moisture and light * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: 2.62 mg/mL (3.65 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source