Pyridostatin trihydrochloride

Overview

Pyridostatin (RR82) trihydrochloride is a G-quadruplex ( G4 ) inducer/stabilizer with a K d of 490 nM. Pyridostatin trihydrochloride also acts as an inhibitor of Zika virus (ZIKV) NS2B-NS3 protease, with an IC 50 of 11.0 μM. Pyridostatin trihydrochloride interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin trihydrochloride exhibits antiproliferative and antiviral activities. Pyridostatin trihydrochloride can be used in studies related to breast cancer , cervical cancer , and Zika virus infection .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Src | Products > Signaling Pathways > Flavivirus | Products > Signaling Pathways > G-quadruplex | Products > Signaling Pathways > Virus Protease

Product Information

• Catalog No.: HY-15176C
• CAS No.: 2517456-88-9
• Molecular Formula: C31H35Cl3N8O5
• Molecular Weight: 706.02
• Purity: 99.85%
• Storage: 4°C, stored under nitrogen, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
• Availability: In-stock

Source

Original product source