Fmoc-L-Lys(N3-Aca-DIM)-OH

Overview

Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Application

Products | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Research Areas > Others | Products > Signaling Pathways > ADC Linkers

Product Information

• Catalog No.: HY-151787
• CAS No.: 2408993-39-3
• Molecular Formula: C35H43N5O6
• Molecular Weight: 629.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source