NNMT-IN-4

Overview

NNMT-IN-4 (compound 38) is a selective, uncompetitive and membrane permeability nicotinamide N-methyltransferase ( NNMT ) inhibitor with IC 50 values of 42 and 38 nM in vitro biochemical and cell-based assays, respectively. NNMT-IN-4 shows favorable PK/PD and safety profiles as well as excellent oral bioavailability and pharmaceutical properties. NNMT-IN-4 can be used as a vivo chemical probe of NNMT .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Fluorescent Dye

Product Information

• Catalog No.: HY-151813
• CAS No.: 2947393-64-6
• Molecular Formula: C9H11N3O
• Molecular Weight: 177.20
• Purity: 99.35%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (28.22 mM); Clear solution
• Availability: In-stock

Source

Original product source