JNK3 inhibitor-3

Overview

JNK3 inhibitor-3 (compound 15g) is a selective, BBB permeable and orally active c-Jun N-terminal kinase 3 ( JNK3 ) inhibitor. JNK3 inhibitor-3 has inhibitory activities to JNK1 , JNK2 and JNK3 with IC 50 values of 147.8, 44.0 and 4.1 nM, respectively. JNK3 inhibitor-3 significantly improves the memory in mouse dementia model. JNK3 inhibitor-3 can be used for the research of Alzheimer’s disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > JNK

Product Information

• Catalog No.: HY-151928
• CAS No.: 2873465-25-7
• Molecular Formula: C26H25N7O2
• Molecular Weight: 467.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source