Glibenclamide (Standard) is the analytical standard of Glibenclamide. This product is intended for research and analytical applications. Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel ( K ATP ) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein . Glibenclamide directly binds and blocks the SUR1 subunits of K ATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy .
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