Glyburide-d 11

Overview

Glyburide-d 11 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein . Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy .

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > CFTR | Products > Signaling Pathways > P-glycoprotein | Products > Signaling Pathways > Isotope-Labeled Compounds | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Mitochondrial Metabolism | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-15206S
• CAS No.: 1189985-02-1
• Molecular Formula: C23H17D11ClN3O5S
• Molecular Weight: 505.07
• Purity: 99.39%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source