DRP1i27

Overview

DRP1i27 is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Dynamin

Product Information

• Catalog No.: HY-152086
• CAS No.: 1453028-33-5
• Molecular Formula: C20H26N6O
• Molecular Weight: 366.46
• Purity: 99.36%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (6.82 mM); Clear solution
• Availability: In-stock

Source

Original product source