LY1

Overview

LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PL pro and M pro with K d values of 1.5 μM and 2.3 μM for M pro C145A protein and PL pro C111A protein, respectively. LY1 potent against the viral proteases, with IC 50 s of 0.12 μM and 0.99 μM against M pro and PL pro . LY1 shows high selectivity over other kinases, human proteases and metalloenzyme.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > SARS-CoV

Product Information

• Catalog No.: HY-152101
• CAS No.: 2883813-32-7
• Molecular Formula: C20H19ClN4O3S
• Molecular Weight: 430.91
• Purity: 98.01%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (5.80 mM); Clear solution
• Availability: In-stock

Source

Original product source