(-)-Bicuculline methobromide

Overview

(-)-Bicuculline methobromide is a potent GABA A blocker. (-)-Bicuculline methobromide alters membrane properties and firing pattern. (-)-Bicuculline methobromide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. (-)-Bicuculline methobromide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current.

Application

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Product Information

• Catalog No.: HY-100783
• CAS No.: 73604-30-5
• Molecular Formula: C21H20BrNO6
• Molecular Weight: 462.29
• Purity: 99.94%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (5.41 mM); Clear solution
• Availability: In-stock

Source

Original product source