(+)-Bicuculline methochloride

Overview

(+)-Bicuculline methobromide is a potent GABA A blocker. (+)-Bicuculline methobromide alters membrane properties and firing pattern. (+)-Bicuculline methobromide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca 2+ -activated K + channels. (+)-Bicuculline methobromide facilitates burst firing via blocking apamin-sensitive Ca 2+ -activated K + current.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GABA Receptor

Product Information

• Catalog No.: HY-100783A
• CAS No.: 53552-05-9
• Molecular Formula: C21H20ClNO6
• Molecular Weight: 417.84
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source